At the recent American Society of Hematology annual meeting, researchers presented preclinical data examining how ...

Figure 1: LSD1 interacts with p53. Because LSD1 does not regulate the activity of p53 in BJ-DNp53 cells in which the DNA-binding ability of p53 is impaired, we reasoned that LSD1 might affect the ...

The most commonly mutated gene in cancer, p53, works by shifting cell metabolism in a way that alters a cell’s identity, researchers at the Sloan Kettering Institute have discovered. More than 50% of ...

Scientists have recently shed some light on exactly why elephants, one of the biggest animals on the planet, paradoxically experience unusually low rates of cancer. The research found these remarkable ...

Scientists at Oregon State University say they have discovered a genetic function that helps the p53 tumor suppressor gene carry out its function and prevent cancer. Finding ways to maintain or ...

St. Jude Children's Research Hospital scientists identified a promising combination approach to treat a rare, but catastrophic pediatric brain cancer called atypical teratoid rhabdoid tumor (ATRT).

RRS1, a ribosome-biogenesis factor previously linked to tumor growth, is now shown to be indispensable for normal human ...