The trefoil peptides spasmolytic polypeptide (SP), intestinal trefoil factor (ITF), and pS2 show lineage-specific expression in the normal gut and are strongly induced after mucosal injury. We ...

Trefoil peptides are small secretory proteins characterized by three intrachain disulfide bonds forming the trefoil motif or P-domain. They are abundantly expressed on mucosal surfaces, especially of ...

The family of trefoil factor peptides brings hope to both research and industry to improve the treatment of chronic disorders. For the first time, a team succeeded in the synthesis and folding of the ...

The fascinating family of trefoil factor peptides brings hope to both research and industry to improve the treatment of chronic disorders such as Crohn's disease. For the first time, a team led by ERC ...

CHATHAM, N.J., Dec. 13, 2021 (GLOBE NEWSWIRE) -- Tonix Pharmaceuticals Holding Corp. (Nasdaq: TNXP) (Tonix or the Company), a clinical-stage biopharmaceutical company, today announced that it has ...

This study evaluated the safety and efficacy of recombinant human intestinal trefoil factor (rhITF) administered as topical oral spray for prevention and treatment of chemotherapy-induced oral ...

CHATHAM, N.J., Nov. 15, 2021 (GLOBE NEWSWIRE) -- Tonix Pharmaceuticals Holding Corp. (Nasdaq: TNXP) (Tonix or the Company), a clinical-stage biopharmaceutical company, today announced that the U.S.

New insights into the molecular mechanisms driving mucus viscosity were have been discovered. A discovery about how mucus thickness is regulated could help to improve airway-clearing treatment options ...

CHICAGO--(BUSINESS WIRE)--Trefoil Therapeutics, a clinical-stage biotechnology company focused on restoring sight to people with corneal diseases, today announced positive Phase 2 results for TTHX1114 ...