The Ink4a/Arf locus encodes two tumour-suppressor proteins that are specified in part by the unprecedented use of alternative reading frames within a common second exon of both genes 1. The first ...

Researchers have broken new ground in the understanding of the MDM2 gene -- which is often overexpressed in cancer -- finding that when it acts with a specific protein, it can lead to cancer cell ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, No. 3 (Jan. 18, 2005), pp. 731-736 (6 pages) The MYCN oncogene is the major negative prognostic marker in ...

Ethnicity & Disease, Vol. 18, Supplement 2: Research Centers in Minority Institutions (RCMI): Current Science (Spring 2008), pp. 1-8 (8 pages) Introduction: Mdm2 inhibits p53 transactivation by ...

Mount Sinai researchers have broken new ground in the understanding of the MDM2 gene--which is often overexpressed in cancer--finding that when it acts with a specific protein, it can lead to cancer ...

While immunotherapy -- a form of treatment that uses the body's immune system to recognize, attack and kill tumor cells -- has given hope to people across the globe, it fails in a significant ...

PROVIDENCE, R.I. [Brown University] -- While immunotherapy -- a form of treatment that uses the body's immune system to recognize, attack and kill tumor cells -- has given hope to people across the ...

We were unable to process your request. Please try again later. If you continue to have this issue please contact [email protected]. Use of alrizomadlin with pembrolizumab appeared to ...

(New York, NY - May 2, 2019) -- Mount Sinai researchers have broken new ground in the understanding of the MDM2 gene--which is often overexpressed in cancer--finding that when it acts with a specific ...