Background: Whether the enteric absorption of the neuraminidase inhibitor oseltamivir is impaired in critically ill patients is unknown. We documented the pharmacokinetic profile of oseltamivir in ...

Though studies evaluating the effects of posture on the absorption of drugs have been conducted, a systematized review revealed critical gaps in methodology. Of 18 original research articles selected ...

Phase I trial of laromustine in combination with infusional ara-C in elderly patients over age 60 with newly diagnosed AML or high-grade MDS ...

Chondroitin sulfate is a heterogeneous polysaccharide in terms of structure, molecular mass, and biological and pharmacological properties. The structure and properties of polysaccharides strongly ...

Purpose: To predict midazolam absorption and pharmacokinetics (PK) after intranasal (i.n.) administration in young children. Methods: The absorption and PK of midazolam were simulated using ...

Drugs are used to prevent, alleviate and treat a variety of illnesses, ranging from the common flu to acute infection to chronic diseases like arthritis. Although the expenditure for drug development ...

In 2018 the US Food and Drug Administration (FDA) passed its stamp of approval on oral capsules of cannabidiol (CBD) for the treatment of seizures. However, nobody quite knew at the time what effect ...