No significant financial relationships to disclose. This is an ASCO Meeting Abstract from the 2004 ASCO Annual Meeting. This abstract does not include a full text component.

Individuals with mutations in the ATM gene develop ataxia-telangiectasia, a neurodegenrative disorder characterized by immunological defects and cancer predisposition. In an Advanced Online ...

Cellular responses to DNA damage are mediated by an extensive network of signaling pathways. The ATM protein kinase is a master regulator of the response to double-strand breaks (DSBs), the most ...

A family history of breast, prostate, and pancreatic cancers is linked to ATM and KRAS gene mutations, despite negative BRCA1/2 results. Genetic testing and counseling are crucial for understanding ...

Twenty-one gene recurrence scores in individuals with breast cancer associated with CHEK2 and ATM germline pathogenic variants. Characteristics and clinical outcome of BRCA germline mutation carriers ...